AMINO ACID DYNAMICS IN URINE OF S. haematobium PATIENTS IN ISHIELU LOCAL GOVERNMENT AREA OF EBONYI STATE, NIGERIA

Hope Chinwe ACHIME, Fabian Chukwuemenam OKAFOR

Abstract


The Amino acid dynamics in urine samples of Schistosoma haematobium patients were studied. The study was to evaluate the possibility and validity of using amino acid patterns recorded in highly, lightly and uninfected urines as diagnostic tool for rapid screening of Schistosomiasis. Paper chromatography was used to separate the different amino acids in the urine samples. The chromatographic method used in this study revealed the existence of 9 essential and 7 non-essential amino acids in the urine samples. It equally showed that histidine, glutamine, serine and proline were absent in all the urine samples. Furthermore the presence of two marker amino acids can be used to identify individuals with heavy infection (cystein) and no infection (methionine).


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References


BARUS, V., TENORA, F. KRACMAR, S. and ZEMAN, L. (1995). Amino acid spectrum of Lingula instestinalis from different Piscean intermediate host. Applied Parasitology, 36(4): 264 – 273.

BARUS, V., KRACMAR, S. and TENORA, F. (1998a). Amino acid spectra of two nematode species parasitizing fishes in the Czech Republic. Helminthologia, 35(1): 7 – 11.

BARUS, V., KRACMAR, S. and TENORA, F. (1998b). Quantitative and qualitative spectrum of amino acids in males and females of three nematode species. Helminthologia, 35(2): 57 – 63.

CUI, Y., LI. J., WANG, Y. and SHANG, Z. (1996). Studies on amino acid components of adult periodic Brugia malayi in two different endemic areas of Guizhou. Chinese Journal of Parasitic Disease Control, 9(4): 285 – 287.

EL-HAWARY, M. F. S., EL-SHOBAKI, F. A., EL-BASSOUSSY, EL. M. M., MOHAREB, S. W., KHASHABA, A. A. and FAHMY, H. A. (1975). Serum and urinary amino acid pattern in different stages of Bilharziasis in Egyptian children before and after specific therapy Egyptian Journal of Physiological Sciences, 2: 69 – 78.

EL-SHOBAKI, F. A., SHAKER, Y. M., EL-HAWARY, M. F. S and SAIF, M. (1980). Serum and urinary amino acid pattern in schistosoma infection among Egyptians. Tropen Medical Parasitology, 31:94 – 98.

HARBONE, J. B. (1973). Amino Acids chemistry and distribution. Pages 168 – 170. In: Phytochemical methods. Chapman and Hall, London.

PLUMMER, D. T. (1979). An Introduction to Practical Biochemistry. 2nd Edition. McGraw Hill. New Delhi.

SOLLMAN, L., ABDELKADER, M. M., ATA, A. A., ABDEL, WAHAB F. and AMARA, S. H. (1986). Urinary amino acid patterns in simple and complicated Bilharziasis. Journal of Tropical Medicine and Hygiene, 72: 166 – 170.


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A Publication of Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Enugu State, Nigeria.